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Cake day: July 1st, 2023

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  • The methods of salmonella mitigation, storing eggs from vaccinated chickens unwashed at room temp or storing washed eggs in the refrigerator, have roughly equal outcomes. There are still many egg-related salmonella outbreaks across Europe each year, roughly equivalent to the US. One method is not superior to another as far as outcomes, they’re just two different systems that already exist and therefore are unlikely to change without a good reason







  • Couple things…why would your dad be mad at you for not finishing a sculpting degree? Is it because he’d feel like he’d wasted money on your completed schooling or because he really wants you to he a sculptor? If the former, pouring more money into this degree would be the wrong course for him too.

    Remember you’re studying in order to be employed after graduation. What do you think you want to do for work? Are there realistic and achievable jobs in that field?




  • OP, I’d urge you to reconsider framing this whole thing as an “extrovert vs introvert” battle. Your boss is demonstrating poor boundaries and disrespectful and inappropriate behavior, and that has nothing to do with whether she’s an I or E on the Myers-Briggs.

    Whether or not you go to HR depends a lot on your company culture. Either way, you need to be documenting specific comments and specific behaviors that are inappropriate first. Every time she asks you an uncomfortable question, especially if it relates to sex, write down what she asked, how you responded (that you declined to answer and asked her to stop asking personal questions), who else was present, and the date/time. Keep this in a personal account, not company. Do NOT go to HR without documentation.

    We don’t know how big your company is, but odds are if she’s a middle manager she’s got people above her already who know she’s a gossip and hate that. If you have any relationship at all with her supervisor, it’s generally viewed as following the chain of command if you bring concerns like this directly to them, as well.










  • protist@mander.xyztoAsklemmy@lemmy.mlHave you ever smoked crack? What was it like?
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    3 months ago

    This is pretty easy to search, but also intuitive when you consider crack is most often smoked vs cocaine being absorbed through your nasal mucosa. Here are a few highlights from this comprehensive review, which also covers the very real socioeconomic differences in use patterns:

    By virtue of its hydrophilicity, cocaine hydrochloride is generally consumed by ‘snorting.’ ‘Crack’ cocaine is generally the only form of cocaine that is smoked—this is due to the fact that cocaine hydrochloride has an elevated boiling point and does not vaporise at the temperatures of combustion.

    ®outes that involve the respiratory system…allow for the stimulant to reach the brain circulation in around 6 to 8 s; the inhalation route presents higher peak plasma concentrations that are reached faster when compared to intranasal administration. It should be noted that, for the intranasal route, the vasoconstrictive properties of cocaine slow down the drug’s own absorption, causing a 60-min delay of peak plasmatic concentrations. In terms of bioavailability, the inhalation route has the greatest bioavailability, which surpasses 90%, while the intranasal route has roughly 80%.

    The abuse and dependence of cocaine is strongly related to the drug’s capacity to induce the release of dopamine within the mesocorticolimbic circuit (also known as the reward system). As the user continues to consume cocaine, desensitization occurs and so larger doses are necessary to induce stimuli of the same magnitude as before, as well as to minimize withdrawal symptoms.

    Another difference of inhalation vs intranasal:

    Smoking ‘crack’ leads to the formation of another biomarker of exposure, AEME, which is the main product of cocaine’s thermal degradation. In vitro and in vivo studies show that AEME appears to have effects on the cardiovascular system, by acting as a muscarinic agonist. Furthermore, neurotoxic effects were also reported for this metabolite.


  • protist@mander.xyztoAsklemmy@lemmy.mlHave you ever smoked crack? What was it like?
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    3 months ago

    Let’s be real though, crack is significantly more addictive than regular cocaine. The high is higher, it lights up all the dopamine receptors in your brain. The high is much shorter, and the crash is much harder, which pushes users to use more to avoid intolerable withdrawal symptoms. Cocaine is “mellower” in pretty much every way. All the bad parts of cocaine use are only magnified in crack use. All this is completely independent of fucked up drug policy